Cp Invite Trial Txt -

-------------------------------------------------------------------------------- 4. STATISTICAL SIGNIFICANCE (Chi-square test) -------------------------------------------------------------------------------- - Arm D vs. Arm A: p < 0.001 (significant) - Arm D vs. Arm B: p = 0.002 (significant) - Arm D vs. Arm C: p < 0.001 (significant) - Arm B vs. Arm A: p = 0.021 (significant) - Arm B vs. Arm C: p = 0.004 (significant) - Arm A vs. Arm C: p = 0.612 (not significant)

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Multi-channel arm reached 50% response by Day 2; single-channel arms required 4-5 days to approach 50%. CP Invite Trial txt

-------------------------------------------------------------------------------- 1. OBJECTIVE -------------------------------------------------------------------------------- To evaluate the effectiveness of targeted invitation methods within a closed population (N=500) for a controlled trial. The primary endpoint is the response rate (acceptance to participate) within 7 days.

PROJECT ID: CP-IT-2026-01 DATE: 2026-04-17 STATUS: FINAL Arm B: p = 0

Average response rate across arms: 46.0%

-------------------------------------------------------------------------------- 6. RECOMMENDATIONS -------------------------------------------------------------------------------- - For closed populations, use multi-channel invitations (email + SMS reminder). - If resources are limited, prefer SMS over email or in-app messaging. - Avoid relying solely on in-app notifications due to low visibility. - Future trials should test timing optimization (e.g., send reminders at 24h instead of 48h). Arm C: p = 0

-------------------------------------------------------------------------------- 7. LIMITATIONS -------------------------------------------------------------------------------- - Closed population may not generalize to open populations. - Incentive ($10) might increase response rates beyond typical real-world levels. - No testing of push notifications vs. in-app banners. - Trial length (7 days) may underestimate late responders.